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   Table of Contents - Current issue
July-September 2019
Volume 4 | Issue 3
Page Nos. 39-61

Online since Tuesday, August 25, 2020

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Principles and clinical applications of computational fluid dynamics in aneurysms of the abdominal aorta p. 39
Haoxuan Kan, Xiaoning Sun, Yuexin Chen, Yuehong Zheng
Computational fluid dynamics (CFD) is a branch of fluid mechanics, referring to the numerical analysis of flow fields. CFD is widely applied in blood flow analysis of abdominal aortic aneurysms (AAAs) and thoracoabdominal aortic aneurysms (TAAAs), providing precision information of the blood flow field and wall stresses of the cardiovascular system. It has the advantages of individualization and noninvasiveness. It is used to predict the risk of growth and rupture of AAA and to evaluate the outcomes after endovascular aortic repair. Focused on AAA and TAAA, this review introduces the principles and clinical research progresses of CFD and looks forward to the future research directions.
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Current application of endovascular interventions in surgical management of carotid body tumor p. 46
Guangchao Gu, Yuehong Zheng
Carotid body tumors (CBTs) are rare neoplasms at the carotid bifurcation. Surgical excision is currently the only curable treatment for CBTs but is associated with high incidence of morbidities and mortality, due to the hyper-vascularity and proximity to carotid vessels and cranial nerves of the tumors. In the last decades, endovascular interventions, including preoperative trans-arterial embolization and carotid stents, have been utilized in surgical excision of CBTs with the attempt to reduce perioperative complications and improve surgical outcomes. However, controversial results have been reported with regard to the efficacy of such techniques. This review summarized the current application of endovascular interventions in surgical treatment of CBTs, with emphasis on their impacts on surgical conducting and perioperative complications.
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Animal models in experimental abdominal aortic aneurysm p. 50
Fang Xu, Xu Zhang, Yuehong Zheng
Abdominal aortic aneurysm (AAA) is a prevalent and potentially life-threatening disease. Many animal models have been developed to simulate the natural history of the disease or test preclinical endovascular devices and surgical procedures. The aim of this review is to describe different methods of AAA induction in animal models and report on the effectiveness of the methods described in inducing an analog of a human AAA. The PubMed database was searched for publications with titles containing the following terms “animal” or ''animal model(s)'' and keywords “research,” “aneurysm(s),” “aorta,” “pancreatic elastase,” “angiotensin,” “AngII” “calcium chloride” or “CaCl2.” Starting date for this search was set to 2010. We focused on animal studies that reported a model of aneurysm development and progression. A number of different approaches of AAA induction in animal models have been developed, used, and combined since the first report in the 1960s. Although specific methods are successful in AAA induction in animal models, it is necessary that these methods and their respective results are in line with the pathophysiology and the mechanisms involved in human AAA development. A researcher should know the advantages or disadvantages of each animal model and choose the appropriate model.
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Renovascular hypertension after laparoscopic adrenalectomy in a young patient p. 56
Chunmin Li, Hualiang Ren, Chuanjun Liao, Wangde Zhang
As 23-Year-old patient suffered from intermittent headache, dizziness and palpitation especially after physical activity for 1 month. A remarked rise of blood pressure as high as 200/100mmHg was found. The CTA revealed a severe stenosis of right renal artery. 5 months ago, he underwent a laparoscopic adrenalectomy. The TVH was totally relived by renal arterial angioplasty.
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Checklists for left subclavian artery reconstruction in thoracic endovascular aortic repair p. 58
Xiaoyu Wu, Kaichuang Ye, Ruihua Wang, Jinbao Qin, Zhiyou Peng, Xinwu Lu
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